Across metazoans, lifespan varies greatly, not only among species but also within the same species. Much effort has been devoted to discovering genetic and abiotic factors associated with longevity in humans, and many lifespan-extending perturbations in model organisms like C.…
Year: 2021
Use of nematodes to study evolutionary biology
Nematodes have been used as model organisms for evolutionary studies. This article highlights the key findings from research on developmental processes, sex determination, dauer formation, vulva development, male tail formation and developmental regulation of gene expression with regards to evolution.…
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Transgenerational Fitness is a great consideration
Dietary restriction (DR),and various forms of it, have been reported in several models including humans to have health benefits. These studies are usually done within a single generation of animals. However, we sometimes lack foresight and do not consider how…
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High-throughput behavioural screen in C. elegans reveals Parkinson’s disease drug candidates
Recent advances in neural networks (NN) and machine learning (ML) algorithms have been beneficial in expediting labour-intensive nematode research. In this paper, the authors assessing nematode behaviour, use a high throughput screen called C. elegans Snapshot Analysis Platform (CeSnAP) which…
Old friends to keep old age away
A lot of people these days suffer from allergic and autoimmune diseases, but this appears to be far more prevalent in wealthy countries. The cause, according to the ‘hygiene hypothesis’ is that people’s immune systems are not primed well enough…