let-7 microRNA absent in many Caenorhabditis nematodes

A recent paper by Nelson and Ambros [1] reports that let-7 heterochronic microRNA is absent in Caenorhabditis species of the japonica group. Research in C. elegans has shown that let-7 plays an essential role during larval to adult transition and mutations…

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Control of life-history trade-off by cis-regulatory mutation in eak-3

A new paper by Billard et al. (DOI: j.cub.2020.08.004) reports that a 92-bp deletion in eak-3 alters steroid hormone dafachronic acid (DA) signaling in C. elegans resulting in increased environmental sensitivity for dauer induction and delayed reproductive growth. The findings…

Continue reading Control of life-history trade-off by cis-regulatory mutation in eak-3