High-throughput behavioural screen in C. elegans reveals Parkinson’s disease drug candidates

Recent advances in neural networks (NN) and machine learning (ML) algorithms have been beneficial in expediting labour-intensive nematode research. In this paper, the authors assessing nematode behaviour, use a high throughput screen called C. elegans Snapshot Analysis Platform (CeSnAP) which…

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Network analysis in aged C. elegans reveals candidate regulatory genes of ageing

Aging is an inevitable process in most multicellular organism that is regulated by both genetic and environmental factors. Multiple pathways have been discovered using the nematode species Caenorhabditis elegans which were then shown to be conserved in other higher eukaryotes.…

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let-7 microRNA absent in many Caenorhabditis nematodes

A recent paper by Nelson and Ambros [1] reports that let-7 heterochronic microRNA is absent in Caenorhabditis species of the japonica group. Research in C. elegans has shown that let-7 plays an essential role during larval to adult transition and mutations…

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C. elegans provide milk to their offsprings through their decomposing bodies

Boroweic et al. (2020) describes the phenomena in which decaying bodies of older C. elegans turn into nutritious fluid for their offsprings using the insulin/IGF-1 insulin pathway. To read more, please click here Post Views: 1,112

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